Roland W Herzog Selected Research

Intramuscular Injections

3/2005	Factor IX variants improve gene therapy efficacy for hemophilia B.
7/2003	Update on gene therapy for hereditary hematological disorders.
4/2003	AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.
7/2002	Influence of vector dose on factor IX-specific T and B cell responses in muscle-directed gene therapy.

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Roland W Herzog Research Topics

Disease

37	Hemophilia B (Haemophilia B) 10/2021 - 04/2002
32	Hemophilia A (Haemophilia) 07/2022 - 04/2004
20	Hemorrhage 01/2022 - 08/2004
11	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 05/2003
10	Glycogen Storage Disease Type II (Pompe's Disease) 12/2017 - 04/2011
7	Anaphylaxis (Anaphylactic Shock) 11/2015 - 04/2010
6	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 10/2007
4	Protein Deficiency 11/2013 - 08/2004
3	Inflammation (Inflammations) 11/2021 - 01/2014
2	Neoplasms (Cancer) 01/2021 - 01/2009
2	Hypersensitivity (Allergy) 11/2019 - 04/2010
2	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2019 - 07/2014
2	Nephrotic Syndrome (Syndrome, Nephrotic) 11/2015 - 11/2013
1	Duchenne Muscular Dystrophy (Muscular Dystrophy, Becker) 11/2021
1	Food Hypersensitivity (Food Allergy) 01/2021
1	Liver Diseases (Liver Disease) 01/2020
1	Peanut Hypersensitivity (Peanut Allergy) 11/2019
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2019
1	Experimental Melanoma 01/2019
1	Persistent Infection 01/2017
1	Hematologic Neoplasms (Hematological Malignancy) 01/2016
1	Primary Immunodeficiency Diseases 01/2016
1	Hemoglobinopathies 01/2016
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 07/2014
1	Disseminated Intravascular Coagulation 01/2014
1	Muscle Weakness 06/2012
1	Neuromuscular Diseases (Neuromuscular Disease) 06/2012
1	Colitis 03/2012
1	Muscular Diseases (Myopathy) 04/2011
1	Infections 03/2011
1	Necrosis 04/2010
1	Neuroinflammatory Diseases 10/2008
1	Severe combined immunodeficiency due to adenosine deaminase deficiency 07/2003

Drug/Important Bio-Agent (IBA)

37	Factor IX (Coagulation Factor IX)FDA LinkGeneric 10/2021 - 04/2002
24	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2004
16	Factor VIII (Coagulation Factor VIII)IBA 07/2022 - 04/2004
15	AntibodiesIBA 01/2022 - 04/2004
12	Blood Coagulation Factors (Coagulation Factor)IBA 01/2022 - 03/2005
9	Pharmaceutical PreparationsIBA 10/2021 - 06/2015
9	AntigensIBA 01/2021 - 08/2004
9	AcidsIBA 01/2016 - 04/2011
6	alpha-Glucosidases (Acid Maltase)IBA 12/2017 - 04/2011
5	GlycogenIBA 01/2016 - 04/2011
5	EnzymesIBA 01/2016 - 03/2005
4	Immunoglobulin E (IgE)IBA 01/2017 - 06/2012
4	GlucosidasesIBA 01/2016 - 06/2012
3	Sirolimus (Rapamycin)FDA Link 07/2022 - 09/2013
3	human GAA protein (Myozyme)FDA Link 10/2015 - 06/2012
2	Prednisolone (Predate)FDA LinkGeneric 11/2021 - 06/2017
2	Cholera ToxinIBA 10/2021 - 04/2015
2	Immunoglobulin G (IgG)IBA 01/2017 - 06/2012
2	Tyrosine (L-Tyrosine)FDA Link 01/2017 - 01/2012
2	Antigen-Antibody Complex (Immune Complex)IBA 01/2017 - 04/2015
2	Codon (Codons)IBA 09/2015 - 01/2012
2	GlucocorticoidsIBA 03/2012 - 04/2010
2	Neutralizing AntibodiesIBA 01/2012 - 01/2012
1	Interleukin-15 (Interleukin 15)IBA 07/2022
1	AutoantibodiesIBA 01/2022
1	Alkaline PhosphataseIBA 11/2021
1	DystrophinIBA 11/2021
1	Ointments (Pastes)IBA 01/2021
1	Cell Surface ReceptorsIBA 01/2019
1	OvalbuminIBA 01/2019
1	IsoantibodiesIBA 01/2018
1	Complementary DNA (cDNA)IBA 01/2016
1	DesminIBA 09/2015
1	B-Cell Activating FactorIBA 06/2015
1	Interleukin-10 (Interleukin 10)IBA 04/2015
1	Immunoglobulins (Immunoglobulin)IBA 04/2015
1	Dacarbazine (DIC)FDA LinkGeneric 01/2014
1	Type 1 Angiotensin ReceptorIBA 01/2014
1	Rituximab (Mabthera)FDA Link 09/2013
1	CytokinesIBA 03/2012
1	LigandsIBA 03/2012
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 03/2012
1	Enzyme Precursors (Zymogens)IBA 01/2012
1	DNA (Deoxyribonucleic Acid)IBA 01/2012
1	LipofectamineIBA 03/2011
1	Bile Acids and Salts (Bile Acids)IBA 01/2009
1	AutoantigensIBA 10/2007
1	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 07/2006
1	Peptides (Polypeptides)IBA 07/2006
1	Nonsense Codon (Nonsense Mutation)IBA 11/2005
1	Adenosine DeaminaseIBA 07/2003
1	N-acetyltalosaminuronic acid (NAT)IBA 07/2002
1	A-factor (Streptomyces)IBA 04/2002

Therapy/Procedure

36	Therapeutics 01/2022 - 05/2003
4	Enzyme Replacement Therapy 10/2015 - 09/2013
4	Intramuscular Injections 03/2005 - 07/2002
3	Injections 01/2020 - 04/2010
2	Immunotherapy 01/2021 - 11/2019
2	Cell- and Tissue-Based Therapy (Cell Therapy) 06/2017 - 07/2014
1	Investigational Therapies (Experimental Therapy) 01/2017
1	Liver Transplantation 01/2017
1	Intravenous Infusions 03/2016
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 07/2014
1	Immunomodulation 09/2013
1	Intranasal Administration 07/2006